Danavir600 is an antiviral drug intended for the treatment of HIV infection in adult patients (in combination with low-dose ritonavir and other antiretroviral drugs). Manufacturer – Hetero Labs Ltd, India. Active substance – Darunavir.
Darunavir is a type 1 HIV protease inhibitor (HIV-1). The drug selectively inhibits the degradation of Gag-Pol HIV polyproteins in virus-infected cells, preventing the formation of high-grade viral particles. Darunavir binds strongly to HIV-1 protease, resistant to mutations that cause resistance to protease inhibitors. Darunavir does not inhibit any of the 13 human cellular proteases studied.